Happy Saffron Plus

Excellent

4.7 out of 5

$44.86 $53.95 SAVE 17%

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Third-Party Tested
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#1 Brand for Brain Health
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Clinical-Grade
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Third-Party Tested
+
#1 Brand for Brain Health
+
Clinical-Grade
+
Third-Party Tested
+
#1 Brand for Brain Health
+
Clinical-Grade
+
Third-Party Tested
+
#1 Brand for Brain Health
+
Clinical-Grade
+
Third-Party Tested
+
#1 Brand for Brain Health
+
Clinical-Grade
+
Third-Party Tested
+
#1 Brand for Brain Health
+
Clinical-Grade
+

Key Ingredients

We only use clinically researched ingredients backed by science.* Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.*

Affron Saffron

Affron Saffron

This highly concentrated, standardized saffron extract is derived from the saffron crocus, a spice traditionally used for over 2,600 years in the Middle East. Clinically studied at a dose of 28 mg per day, it has been shown to support a balanced mood, reduce feelings of anxiousness, and promote emotional well-being in both adults and adolescents.* Saffron's active compounds help modulate neurotransmitters like serotonin and dopamine,contributing to its mood-enhancing effects.*

LONGVIDA Curcumin

LONGVIDA Curcumin

Turmeric root has been used in traditional Asian medicine for over 2,600 years to support mood and overall well-being.* Its active compound, curcumin, has powerful antioxidant and anti-inflammatory properties that helpprotect brain cells and support emotional balance.* This highly absorbable form of curcumin has shown strong results in clinical studies at doses of 400 mg or more,improving mood, reducing stress, and supporting joint and immune health.* Its enhanced absorption ensures optimal effectiveness in the body.*

Zinc

Zinc

Zinc is an essential mineral involved in over 100 enzymes that support vital processes in the body.* It plays a key role in the healthy development and function of the eyes,brain, spinal cord, thymus gland, and digestive system.*Zinc is crucial for maintaining strong immunity, repairing and renewing skin and hair, and preserving DNA structure.* By supporting these systems, zinc promotes overall growth, healing, and resilience, making it vital for both physical health and immune defense.*

Supplement Facts

70% of dogs over

Supported by Clinical Research

SAFFRON SUPPORTS POSITIVE MOOD +

Clinical studies in healthy adults

affron® saffron extract has been shown in human trials to help support mood and emotional well-being.

SAFFRON HELPS PROMOTE CALM +

Clinical research in adolescents

Controlled research shows saffron extract can help encourage calmness and balanced mood in youth.

CURCUMIN SUPPORTS HEALTHY THINKING +

Studied in older adults

Research shows curcumin supplementation supports cognitive performance and healthy mood in aging populations.

CURCUMIN HELPS MEMORY & FOCUS +

Clinical study in adults

A published trial found curcumin supported memory, attention, and overall brain health in non-demented adults.

ZINC HELPS SUPPORT MOOD +

Human & animal research

Studies suggest maintaining healthy zinc levels plays a role in emotional balance and calmness.

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Happy Brain, Healthy Body

Better Mood, Memory & Sexual Health

Happy Saffron Plus® isn’t just doctor-developed, it's doctor-recommended, loved in 217 countries, and backed by over 25 human studies.*

In the largest clinical trial on saffron and mood to date, 72% of participants taking affron® (the exact extract in this formula) experienced meaningful mood improvement, many in just 5 weeks.*

With Longvida® curcumin for focus and memory, plus zinc glycinate for mood and sexual health, this 3-in-1 formula delivers fast, feel-good results - naturally.*

Expert Reviews

Dr. Daniel Amen

Dr. Daniel Amen

"This is one of my favorite formulas. Saffron has been studied for centuries, but the form we use—affron®—is backed by modern clinical trials. I take Happy Saffron Plus® daily because it works. Better mood, better memory, better overall brain health—naturally."

Founder BrainMD & Amen Clinics
Dr. Jonny Bowden PhD, CNS

Dr. Jonny Bowden PhD, CNS

"This formula contains ingredients I used to recommend individually but BrainMD combines them in clinically validated doses for even better results. I’ve seen it help patients feel more emotionally balanced and mentally sharp within weeks."

Board Certified Nutrition Specialist
Peggy Perez

Peggy Perez

"Saffron has long been used in ancient medicine, but affron® takes it to a new level. It’s clinically backed, bioavailable, and when paired with Longvida® curcumin and zinc glycinate, it becomes a powerhouse for brain health and emotional wellness."

Brain Health Professional NASM CPT & CES IIS Health Coach
Erica Williams

Erica Williams

"I love Happy Saffron Plus®! I was able to be off all anxiety/depression medications after 23 years. It works on multiple levels—mood, focus, and energy. It’s NAME-developed, rooted in science, and something I recommend regularly to my clients."

Brain Health Professional Elite Brain Health Coach Life Coaching & Consulting Associates
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Healthier, Happier YOU*

Clinically Dosed. Doctor Trusted. Loved Worldwide.*

Most saffron supplements stop at mood. Happy Saffron Plus® goes further, targeting mood, memory, libido, stress, and sleep with three highly bioavailable, research-backed ingredients that work better together.*

✔ affron® Saffron Extract: The only saffron with 10+ human clinical studies on mood, stress, and sleep.

✔ Longvida® Curcumin: 285x more bioavailable than standard curcumin and clinically shown to enhance memory within hours.*

✔ Zinc Glycinate: An essential mineral that supports mood, hormones, and brain health.*

This formula isn’t just well-dosed, it’s strategically dosed. Each ingredient amplifies the effects of the others for a synergistic boost you can feel, without hormones, SSRIs, or side effects.*

What To Expect

What To Expect

Day 1 - Instant Memory Boost

Clinical research shows that 400 mg of Longvida® curcumin—the same amount used in Happy Saffron Plus®—can boost working memory by 16% within just one hour of your first dose.*

Week 4 - Sweet Dreams & Bright Moods

In just 4 weeks, 28 mg/day of affron® saffron helped improve mood and sleep, and reduced stress by 41% in clinical trials.*

Week 12 - More Happiness, Less Anxiousness

In 12 weeks, 28 mg/day of affron® saffron significantly improved mental health, reduced occasional anxiousness by 33% and low mood by 32%.*

Long-Term - Cumulative Brain & Body Benefits

Expect better mood, memory, and sexual health with continued use.*

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What Our Customers Are saying...

Very good 4.7/5 based on 1046 verified reviews

Get Started Today

A happier, healthier, fuller life begins with better brain health.

A SMARTER WAY TO SUPPLEMENT

Frequently Asked Questions

HOW DO I TAKE HAPPY SAFFRON PLUS? +

It’s recommended that adults take 3 capsules daily between meals.*

CAN CHILDREN TAKE HAPPY SAFFRON PLUS? +

Children ages 4-18 years can take 1 capsule per 40 pounds body weight, maximum 3 capsules daily.*

IS HAPPY SAFFRON PLUS SUITABLE FOR VEGANS? +

Yes. Happy Saffron Plus® is suitable for vegans, especially those seeking to improve their mood.*

IS IT POSSIBLE TO GET HOOKED ON THIS PRODUCT? +

As with other BrainMD products, this is a dietary supplement, not a drug.* It isn’t habit-forming.*

DOES THIS SUPPLEMENT CONTAIN ALLERGENS? +

It is free from dairy, gluten, sugar, corn, nuts, eggs, yeast, and artificial flavorings or colorings.* It does contain very small levels of soy (non-GMO).*